Detalhe da pesquisa
1.
Molecular docking and oxidation kinetics of 3-phenyl coumarin derivatives by human CYP2A13.
Xenobiotica
; 51(11): 1207-1216, 2021 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-33703988
2.
In vitro sulfonation of 7-hydroxycoumarin derivatives in liver cytosol of human and six animal species.
Xenobiotica
; 50(8): 885-893, 2020 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-31903849
3.
Coumarin-Based Profluorescent and Fluorescent Substrates for Determining Xenobiotic-Metabolizing Enzyme Activities In Vitro.
Int J Mol Sci
; 21(13)2020 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32630278
4.
Development of new Coumarin-based profluorescent substrates for human cytochrome P450 enzymes.
Xenobiotica
; 49(9): 1015-1024, 2019 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-30272491
5.
Metabolism of Scoparone in Experimental Animals and Humans.
Planta Med
; 85(6): 453-464, 2019 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-30736072
6.
Molecular Docking-Based Design and Development of a Highly Selective Probe Substrate for UDP-glucuronosyltransferase 1A10.
Mol Pharm
; 15(3): 923-933, 2018 03 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29421866
7.
Comparison of In Vitro Hepatic Scoparone 7-O-Demethylation between Humans and Experimental Animals.
Planta Med
; 84(5): 320-328, 2018 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-28950382
8.
Blocking oestradiol synthesis pathways with potent and selective coumarin derivatives.
J Enzyme Inhib Med Chem
; 33(1): 743-754, 2018 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-29620427
9.
A liquid chromatography-tandem mass spectrometry analysis of nine cytochrome P450 probe drugs and their corresponding metabolites in human serum and urine.
Anal Bioanal Chem
; 409(1): 251-268, 2017 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-27734142
10.
Inhibitory effects and oxidation of 6-methylcoumarin, 7-methylcoumarin and 7-formylcoumarin via human CYP2A6 and its mouse and pig orthologous enzymes.
Xenobiotica
; 46(1): 14-24, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-26068522
11.
[Drug therapy and the most common drugs for childhood psychiatric disorders]. / Lasten psykiatristen häiriöiden lääkehoito ja tavallisimmat lääkkeet.
Duodecim
; 132(10): 943-50, 2016.
Artigo
em Finlandês
| MEDLINE | ID: mdl-27382830
12.
Time-Dependent Inhibition of CYP2C19 by Isoquinoline Alkaloids: In Vitro and In Silico Analysis.
Drug Metab Dispos
; 43(12): 1891-904, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26400396
13.
Ultrafast protein structure-based virtual screening with Panther.
J Comput Aided Mol Des
; 29(10): 989-1006, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26407559
14.
Rational design of novel CYP2A6 inhibitors.
Bioorg Med Chem
; 22(23): 6655-6664, 2014 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25458499
15.
Prodrugs--from serendipity to rational design.
Pharmacol Rev
; 63(3): 750-71, 2011 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-21737530
16.
Design, synthesis, and evaluation of novel cyclic phosphates of 5-aminosalicylic acid as cytochrome p450-activated prodrugs.
Mol Pharm
; 10(2): 532-7, 2013 Feb 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-22937971
17.
Pinoresinol stimulates keratinocyte proliferation and downregulates TNF-α secretion in peripheral blood mononuclear cells: An experimental in vitro study.
Health Sci Rep
; 6(1): e998, 2023 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-36544622
18.
Metabolism of bilirubin by human cytochrome P450 2A6.
Toxicol Appl Pharmacol
; 261(1): 50-8, 2012 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22465937
19.
CYP2A6: genetics, structure, regulation, and function.
Drug Metabol Drug Interact
; 27(2): 73-88, 2012 May 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-22706231
20.
A Comprehensive Evaluation of Sdox, a Promising H2S-Releasing Doxorubicin for the Treatment of Chemoresistant Tumors.
Front Pharmacol
; 13: 831791, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35321325